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王栋
职称:教授
单位:新疆大学药学院
社会任职:研究生教育评估监测专家库专家;执业药师;新疆科技厅项目评审专家;天津市科委项目评审专家;美国化学会及中国化学会会员等

个人简介

王栋,博士,新疆大学化学学院教授,Letters in Drug Design & Discovery期刊青年编委(2025-);Molecules期刊客座编辑(2025-);Frontiers in Chemistry期刊评审编辑(2022-)等。以唯一第一作者或唯一通讯作者已发表50余篇SCI 论文,包括20余篇一区论文、3 篇影响因子10 以上的论文、3篇封面论文、1篇VIP论文以及2 篇综述。此外,授权40余项专利。作为项目第一负责人主持两项国家级项目,四项省部级项目及一项横向项目。

教育经历

  • 2006/08~2011/05 美国路易斯安那州立大学(LSU),有机化学专业,博士,导师:William E. Crowe
  • 2003/09~2006/03 北京理工大学,应用化学专业,工学硕士,导师:朱长进
  • 1999/09~2003/07 北京理工大学,化学工程与工艺专业,工学学士

学术贡献

  • 1. An Yan, Tong Han, Futian Mi, Turghun Muhammad and Dong Wang*. Solvent-Free Organocatalytic Synthesis of Fluorescent N-Alkylated Pyridones: A Metal/Base-Free Migration Strategy. Advanced Synthesis & Catalysis, 2026, ASAP, DOI: 10.1002/adsc.70335.
  • 2. Hua Xiao, Reziyamu Wufuer, and Dong Wang*. Formal Synthesis of Ortho-Cyanated N-Heterocycles via Direct, Metal-Free Cyanation of N-Oxides Under Benign Conditions. Molecules, 2026, 31(2), 276.
  • 3. Mingyue Zhou, Bolong Xu, Dong Wang, Zhaofeng Wu,* Lu Zhang,* and Sheng Cai. Wearable Acetone Gas Sensor Enabled by Quantum Dot-Sensitized Flower-like Ti3C2Tx for Metabolic Monitoring. ACS Sensors, 2026, 11, 157-167.
  • 4. Liqing Xu, Xuemeng Wang, Yunyun Liu and Dong Wang*. Unlocking a Grignard Cascade: Three-Component Access to Complex Polycyclic Architectures from Quinolines. Organic Letters, 2025, 27 (49), 13475-13479.
  • 5. Xu Wang, An Yan, Hua Xiao, Weiwei Xiao, Liqing Xu and Dong Wang*. C3-H Trifluoroacetylation of Quinolines and Pyridines: Access to Heteroaryl Ketones, Carboxylic Acids and Amides. Organic Letters, 2025, 27 (22), 5625-5631.
  • 6. Longteng Fang, Liping Xu, Marhaba Kader, Tingting Ding, Shiyang Lu, Dong Wang*, Amit Raj Sharma and Zhiwei Zhang*. Salt-Adapted Microorganisms: A Promising Resource for Novel Anti-Cancer Drug Discovery. Marine Drugs, 2025, 23,296.
  • 7. Ao Li, Yueting Yu, Zhiwei Zhang, Reziyamu Wufuer, Dong Wang* and Lu Zhang*. Pd-modified MXene enabled electrochemical sensing platform for ratiometric detection of acetylcholinesterase inhibitors via modulation effect of Prussian blue. Analytica Chimica Acta, 2025, 1376, 344625.
  • 8. Lu Zhang*, Mingyue Zhou, Fanxing Meng, Jinyu Bai, Dong Wang, Mingcong Tang*, Zhaofeng Wu*. Recent advances in chemiresistive gas sensor for acetone detection: Focus on room temperature. Trends in Analytical Chemistry, 2025, 187, 118213.
  • 9. Danyi Liu, Fenlian Xu, Tong Han, Keyume Ablajan and Dong Wang*. Sustainable Synthesis of Heteroaryl Ethers from Azine N-Oxides via Phosphoramide Catalysis. Green Chemistry, 2025, 27 (26), 7788-7794. (Selected as Front Cover Paper)
  • 10. Marhaba Kader, Liping Xu, Longteng Fang, Reziyamu Wufuer, Minwei Zhang, Nan Wei, Dong Wang* and Zhiwei Zhang*. The Antimicrobial Extract Derived from Pseudomonas sp. HP-1 for Inhibition of Aspergillus flavus Growth and Prolongation of Maize Seed Storage. Foods, 2025, 14, 1774.
  • 11. Yuze Shi, Xuemeng Wang, Weiwei Xiao, Jiaxin Li and Dong Wang*. Development of Water-Soluble Nicotinamide Coenzyme Biomimetics for Improved Catalytic Efficiency. ChemistrySelect, 2025, 10 (16), e202501957.
  • 12. Liqing Xu#, Xu Wang#, Dezhi Yang, Xiaolong Yang and Dong Wang*. Direct C3-H Alkylation and Alkenylation of Quinolines with Enones. Angewandte Chemie International Edition, 2025, 64 (1), e202416451.
  • 13. Lu Zhang,* Ao Li, Mingping Shen, Zhiwei Zhang, Reziyamu Wufuer and Dong Wang*. Palladium–platinum bimetallic modified MXene nanozyme for highly sensitive detection of active substances with acetylcholinesterase inhibitory effect. Talanta, 2025, 282, 127020.
  • 14. 郭安路,开丽比努尔·艾山,许利清,王栋*。1,8-萘啶酮类化合物的高效合成,广东化工,2024,51(13),21-24.
  • 15. Kaijuan Wang, Chengcheng Gong, Weiwei Xiao, Ablimit Abdukader and Dong Wang*. Accessing 1,8-Naphthyridone-3-Carboxylic Acid Derivatives and Application to the Synthesis of Amfonelic Acid. Journal of Organic Chemistry, 2024, 89 (8), 5811-5824.
  • 16. Changna Bu, Kaijuan Wang, Chengcheng Gong and Dong Wang*. Green and Fast 2-Aryloxylation/Amination of Quinolines. Green Chemistry, 2024, 26 (8), 4659 - 4664.
  • 17. Xiaolong Yang, Danyi Liu and Dong Wang*. Accessing Tetrahydroquinaldic Amide and Homoproline Derivatives by Dearomative Difunctionalization of Heteroaromatics. Asian Journal of Organic Chemistry, 2024, 13(1), e202300559.
  • 18. Qian Ma, Yuze Shi and Dong Wang*. Phosphonium Salt-Promoted C2–H Functionalization of Heterocyclic N-Oxides. Organic Letters, 2023, 25(51), 9181-9185.
  • 19. 王凯娟,许利清,王栋*。吡啶及喹啉氮氧化物C2-H键官能团化反应的最新进展,中国科学:化学,2023, 53 (8), 1369-1376.
  • 20. Dong Wang*, Liqing Xu, Shixin Zheng and Xiaolong Yang. Transition-Metal-Free Regioselective Direct C2, C4 Difunctionalization and C2, C4, C6 Trifunctionalization of Pyridines. Advanced Synthesis & Catalysis, 2022, 364 (16), 2720-2728.
  • 21. Dong Wang, Mustafa Tezeren, Hussein Abou-Hamdan, Peng Yu, Canan G. Nebigil and Laurent Désaubry*. Flavaglines: Their Discovery from Plants Used in Traditional Chinese Medicine, Synthesis, and Drug Development Against Cancer and Immune Disorders. Current Chinese Chemistry, 2022, 364 (16), 2720-2728.
  • 22. Shixin Zheng, Dong Wang*, Mindong Huang and Peng Yu*. Rapid Generation of Tetrahydropyridines and Tetrahydroquinolines by Dearomative Cyanation/Grignard Addition. Chemistry-An Asian Journal, 2022, 17, e202200077.
  • 23. 王栋,阿布力米提·阿布都卡德尔。基于粉笔教学的有机化学教学改革,广东化工,2021,48(8),294-295.
  • 24. Dong Wang*, Laurent Désaubry, Gaoyu Li, Mindong Huang and Shixin Zheng. Recent Advances in the Synthesis of C2‐Functionalized Pyridines and Quinolines Using N-oxide Chemistry. Advanced Synthesis & Catalysis, 2021, 363 (1), 2-39. (Selected as VIP and Front Cover Paper)
  • 25. Dong Wang, Redouane Tabti, Sabria Elderwish, Amel Djehal, Nora Chouhad, Franck Pinot, Peng Yu, Canan G. Nebigil, Laurent Désaubry. SFPH proteins as therapeutic targets for a myriad of diseases. Bioorganic & Medicinal Chemistry Letters, 2020, 30 (22), 127600.
  • 26. Xin Jin, Jianling Xie, Michael Zabolocki, Xuemin Wang, Tao Jiang, Dong Wang, Laurent Désaubry, Cedric Bardy, Christopher G Proud. The prohibitin-binding compound fluorizoline affects multiple components of the translational machinery and inhibits protein synthesis. Journal of Biological Chemistry, 2020, 295(29), 9855-9867.
  • 27. Tian Zhao, Yujie Liu, Yanfei Hao, Wei Zhang, Li Tao, Dong Wang, Yuyin Li, Zhenxing Liu, Edward A McKenzie, Qing Zhao*, Aipo Diao*. Esomeprazole inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis. Investigational New Drugs, 2021, 39, 337-347.
  • 28. Dong Wang*, Mindong Huang, Gaoyu Li, Shixin Zheng, Peng Yu. Scalable Synthesis of a Tetrasubstituted 7-Azabenzofuran as a Key Intermediate for a Class of Potent HCV NS5B Inhibitors. Tetrahedron, 2020, 76 (48), 131642.
  • 29. Linru Dong, Xinyue Ma, Yu Fan, Dong Wang*. A One‐Pot Dearomative Approach to C4‐Alkylated Tetrahydropyridines and Tetrahydroquinolines. Asian Journal of Organic Chemistry, 2020, 9(10), 1571-1575.
  • 30. Lianbo Zhao, Lei Hao, Yupeng Fu, Yan Cheng, Guojun Pan, Laurent Désaubry, Peng Yu*, Dong Wang*. Accessing 1,8-Naphthyridones by Metal-Free Regioselective Amination of Pyridine N-oxides/Acid-Mediated Cyclization. Advanced Synthesis & Catalysis, 2020, 362, 3841-3845.

工作经历

  • 2024/04~2025/01 新疆大学,药学院,副院长

  • 2022/05~2025/01 新疆大学,药物研究所,副所长

  • 2021/12~至今 新疆大学,化学学院,教授

  • 2021/01~2021/12 新疆大学,化学学院,副教授

  • 2014/12~2021/01 天津科技大学,生物工程学院,副教授

  • 2012/08~2014/12 天津长森药业有限公司,研发部助理主任及主任级研究员

  • 2011/05~2012/08 天津药明康德新药开发有限公司,合成部组长及高级研究员II

  • 2007/06~2011/05 美国路易斯安那州立大学化学系助教及助研Chem 2364 有机化学实验,Chem 1212 大学化学实验